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CD30-L rabbit pAb2

簡要描述：SourceRabbitApplicationsWB,ELISAReactivityHumanDilutionWB:1:500-1:2000

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2024-11-11
  • 訪  問  量：84

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詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CD30-L Polyclonal Antibody detects endogenous levels of CD30-L protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF8. AA range:131-180

  • Uniprot No

    P32971

  • Alternative names

    TNFSF8; CD30L; CD30LG; Tumor necrosis factor ligａnd superfamily member 8; CD30 ligand; CD30-L; CD153

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    tumor necrosis factor superfamily member 8(TNFSF8) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligａnd family. This cytokine is a ligａnd for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

  • Other

    TNFSF8, Tumor necrosis factor ligａnd superfamily member 8

  • Mol.Wt (Da)

    26017

  • Concentration

    1 mg/ml

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